![]() albicans Ess1 is essential for growth and morphogenetic switching. We are investigating a PPIase called Ess1, which is conserved in all major human pathogenic fungi. Among potential targets are enzymes known as peptidyl-prolyl cis/ trans isomerases (PPIases) that catalyze isomerization of peptide bonds preceding proline. albicans strains makes it important to identify new antifungal drug targets. ![]() Candida albicans is a fungal pathogen that causes potentially fatal infections among immune-compromised individuals.
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